At DEMO SA, one of the world's largest pharmaceutical manufacturers in injectable facilities, we are excited to kick-off our Biotechnology project in Athens.

The field of Biotechnology is bringing about fascinating developments in medicine, treatments, and healthcare, as new, effective medicines are being produced from extremely complex natural compounds, with a biological origin. Demo leads the way in the Greek pharmaceutical market with major investments in Biotechnology;

• We are building a prototype unit for the development of monoclonal antibodies
• We are creating a contemporary Research and Development Center for biotechnology
• We are starting research for three finished pharmaceutical products with monoclonal antibodies
• We are establishing a Biotechnology Academy to train young scientists. Biotechnology is becoming part of our lives.

As a result, we are currently looking for a high caliber USP DEV Scientist

Main duties and responsibilities:

• Perform upstream processing development and process optimization activities.
• Participate in the technology transfer from contract manufacturing organization and may perform duties in the plant.
• Participate in the process scale-up from laboratory to pilot and commercial scale.
• Participate and perform process scale down model development and process characterization studies.
• Assist in risk management strategies, adoption of newer technologies for upstream functional activities.
• Review all process related documentation at every stage: process development, transfer, scale-up, scale-down, characterization and manufacturing.
• Set up, execute, and provide technical support during process development and manufacturing activities.
• Assist in the design and execution of experimental plans to understand the process and its robustness (Identification and characterization of Critical Process Parameters and their link with Critical Quality Attributes)
• Prepare technical documents, updates to senior management and manage the cell culture operations for enabling routine activities
• Prepare investigation reports on deviations from the GMP manufacturing process
• Responsible for experimental data analysis using statistical tools and documentation.
• Experienced in the DoE principles and able to apply them in the process development experiments
• Abilities to seamlessly work with multiple cross functional teams to deliver on program timelines.

• MSc in biology, biotechnology, or related field.
• PhD degree in a field related to biotechnology, bioengineering, biochemistry, or cell-culture will be highly appreciated
• 1-3 years in upstream processing of biotherapeutics (biosimilars and monoclonal antibodies preferred)
• Sound knowledge of regulations required for development of biotech products, preferably in biosimilars development
• Excellent communication skills both verbal and written
• Strong problem-solving attitude, critical thinking
• Resilience and ability to work under pressure

The Company offers competitive remuneration, continuous learning and development opportunities, and a friendly and challenging working environment.